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The CLP model of sepsis is the most broadly applied of such models worldwide and is regarded the finest model to mimic human sepsis32. It is a polymicrobial infection that provokes systemic inflammation, with many organ harm, which includes the use of antimicrobial therapy and volume resuscitation5,33. In our laboratory, we have considerable expertise with this model5,9,26,28,34. As previously described28, for indirect quantification of the recruitment or transmigration/activity of neutrophils in the lungs, we measured the enzyme myeloperoxidase activity, expressed in arbitrary units per gram. The completed product is an productive greenish/brownish sealant the bees use to fuse unwanted openings...